AgeDefyRX

(245 Google Reviews)

Anti-Aging Prescription Cream

Reduce and prevent wrinkles and fine lines via a cream freshly compounded with a proven blend of tretinoin, niacinamide, and azelaic acid.

Wrinkles

Dark Spots

Uneven Skin

Large Pores

  • Azelaic Acid 5%/Tretinoin 0.03%/Niacinamide 4% 30gm

    Additional Ingredients: macadamia oil, jojoba oil, vitamin E, phosphatidylcholine, and dimethicone

    -Hypoallergenic

    -Formulated without Parabens and Petrolatum

    Important drug information

  • –  Speeds up skin cell turnover; 

    Treats wrinkles, fine lines & acne

    Reduces hyperpigmentation while hydrating the skin

    Promotes a smoother and more even skin texture

    Dermatologist-formulated with concentrated prescription ingredients

    Freshly compounded at the pharmacy, ensuring maximum efficacy

  • Apply one pump to your fingertips and gently massage onto your face, after cleansing your face. Use a gentle hydrating moisturizer after applying.

    Be sure to wear a mineral-based sunscreen with minimum SPF 30 daily, as your skin will be extra sensitive to sun exposure.

    • Results typically seen in 8 weeks with consistent use.
    • One bottle contains approximately a 2-month supply.

60-day formula


Start consultation

Before & After Using AgeDefyRX

“I have been using AgeDefyRX for a few months and am seeing a big improvement!  My acne is finally getting better!!  Wish I had known about this a lot sooner.”

Katy C.

“This prescription-strength product works for me while others I tried did not.”

Matthew J.

“I have been using AgeDefyRX for a few months and am seeing a big improvement!  I am seeing lesser wrinkles!!  Wish I had known about this a lot sooner.”

Susie L.

What is AgeDefyRX?

AgeDefyRX is prescription multifactorial advanced skincare cream for wrinkles, dark spots, and uneven skin tone. Reduce and prevent wrinkles and fine lines via a cream freshly compounded with a proven blend of tretinoin, niacinamide, and azelaic acid.

AgeDefyRX is dermatologist-formulated and developed by experts certified by the American Board of Dermatology (ABD) and members of the American Academy of Dermatology (AAD).

Penetrates the lipid bilayer of the skin for maximum absorption

Visibly reduces redness wrinkles through a combination of tretinoin, niacinamide, and azelaic acid

Targets the root causes of skin aging to reduce the appearance of wrinkles and restore a smoother texture

Shop our Everyday Essentials

How does AgeDefyRX compare?

Product Features
Expertise Created by Board Certified Dermatologists
Care Hands-on care and check-in with your clinician anytime, anywhere
Accessibility Your RX products are delivered to your door on a monthly basis
Doctor Visit Cheaper doctor visits to get your prescription
Treatment Cheaper prescription treatment options
Consultation Consult with your prescriber to discuss your progress within 24 business hours
DoctorDerm
Included
Less than $2/day
Traditional Rx
$200+
$400–$1000+

How does AgeDefyRX compare?

Product Features
Expertise Created by Board Certified Dermatologists
Care Hands-on care and check-in with your clinician anytime, anywhere
Accessibility Your RX products are delivered to your door on a monthly basis
Doctor Visit Cheaper doctor visits to get your prescription
Treatment Cheaper prescription treatment options
Consultation Consult with your prescriber to discuss your progress within 24 business hours
DoctorDerm
Included
Less than $2/day
Traditional Rx
$200+
$400–$1000+

AgeDefyRX Benefits

Penetrates the lipid bilayer of the skin to improve the delivery of ingredients deep into the skin for maximum efficacy

Formulated with a carefully calibrated ratio of clinically approved medical ingredients combined for optimal results

Visibly reduces redness through a combination of anti-inflammatory actions, specifically targeting and killing Demodex mites, which causes rosacea

Decreases blood flow to the skin’s surface, thereby diminishing redness and improving the appearance of rosacea-affected skin

The Professional Dermatology Care You Need

Dr. Cheryl Bansal is founder and Chief Medical Officer of DoctorDerm. With 15 years of experience in medical, surgical, cosmetic, and pediatric dermatology, Dr. Bansal believes that skin care should be effective, accessible, and convenient.

DoctorDerm was born from this spirit, and our mission is to educate our patients and inspire confidence so we can all reach our potential.

Getting a DoctorDerm Prescription is Easy

Answer Questions for Fast Review

Our team of medical professionals, led by Board-Certified Dermatologists will review your answers to assure AgeDefyRX is right for you.

Freshly Compounded

Top-quality ingredients are freshly combined just before shipping, ensuring maximum potency and efficacy.

Shipped to You

Your treatment is delivered to your door, so you can see results without visiting a dermatologist or waiting in pharmacy lines.

Formulated for Deep Dermal Delivery

DoctorDerm compounds prescription ingredients with synergistic lipids that facilitate their absorption and activation at the right dermal layers. Our formulations are proprietary and not available via other dermatologists.

PATIENT DRUG EDUCATION


  • Compounded Drug
    ● This prescription was specifically compounded in our pharmacy for you at the direction of your prescriber.
    ● Compounded medications are not FDA-approved but include active ingredients sourced from FDA registered facilities.
    ● If you notice any changes in its appearance, color, or consistency, please contact us or your prescriber immediately before using the medication.
    ● For any questions about this compounded medication, ask your health care provider or pharmacist. We prioritize the quality and safety of compounded medications and are available to address your concerns.

    Active Ingredients
    Your compounded product may contain one or more of the following ingredients:
    Azelaic Acid (pronounced ay-zuh-lay-ik as-id) is used to help clear pores of bacteria, reduce inflammation caused by acne and rosacea while evening out skin tone.
    Clindamycin (pronounced klin-da-mye-sin) is used to help slow and stop the growth of bacteria on the skin and control acne.
    Dapsone (pronounced dap-sown) is used to help stop the growth of bacteria on the skin and reduce inflammation.
    Ivermectin (pronounced ai-vr-mek-tn) used to help reduce facial redness and inflammation caused by rosacea.
    Niacinamide (pronounced nye-a-sin-a-mide) is a form of vitamin B3 used to help with skin brightening and smooth your overall skin texture.
    Oxymetazoline (pronounced ak-see-meh-tuh- zow-leen) is used to narrow blood vessels under the skin to reduce facial redness caused by rosacea.
    Tretinoin (pronounced truh-ti-now-in) is a retinoid used to help reduce the appearance of wrinkles, fine lines and oil production.

    Before using this medication, talk to your health care provider if you:
    ● Have high sensitivity to the sun or spend a lot of time in the sun.
    ● Have eczema, as this product may cause irritation.
    ● Have a glucose-6-phosphate dehydrogenase deficiency (G6PD).
    ● Have higher than normal levels of methemoglobin in your blood (methemoglobinemia).
    ● Have a history of heart disease or blood pressure problems. heart attack, stroke, and/or blood vessel or blood flow problems.
    ● Have a history of Raynaud’s syndrome, Buerge disease, or Sjogren’s syndrome.

    Use in pregnancy:
    ● Do not use this medication if you are pregnant or breastfeeding and your medication contains Tretinoin, Dapsone, Oxymetazoline, and/or Ivermectin.
    ● Tell your health care provider if you are pregnant, plan on getting pregnant, or if you are breastfeeding.

    Use in children and adolescents:
    ● Do not use in children under 12 years of age.

    Interactions with this medication:
    There are products that may interact with your medication that can change its effectiveness and increase the risk for serious side effects. Before starting this medication, talk to your health care provider for more details about how this medicine might interact with other products and if you’re using any of these products:
    ● Other topical medications or OTC products.
    ● Medicated, abrasive or drying soaps, cleansers and cosmetics.
    ● Oral dapsone.

    This is not a complete list of possible interactions. It is important to keep a list of all products you currently use and talk to your health care provider before adding anything new to avoid potential interactions. Ask your health care provider or pharmacist for more details about how this medicine might interact with other products.

    What to know while using this medication
    Common side effects:
    The most common side effects in adults include:
    ● Increased sun sensitivity.
    ● Skin irritation, redness, or blisters at the site of application.
    ● Skin dryness, itching, and peeling.

    Serious side effects:
    Stop using this medication and talk to your health care provider or seek medical attention right away if you develop:
    ● Signs of a severe allergic reaction such as:
    ● Swelling of the mouth, throat, and/or tongue.
    ● Swelling of the eyes.
    ● Swelling of the hands and/or feet.
    ● Difficulty breathing or swallowing.
    ● Itchy skin.
    ● Raised, red skin rash.
    ● Diarrhea or bloody diarrhea.
    ● Colitis, or inflammation of the colon.
    ● Signs of hemolytic anemia, a breakdown of red blood cells, such as:
    ● Back pain, fever, and/or shortness of breath.
    ● Dark brown urine.
    ● Yellow or pale skin.
    ● Tiredness or weakness.
    ● Signs of methemoglobinemia such as:
    ● Grey or blue lips, nail beds, or inside of your mouth.
    ● Worsening rosacea.
    ● Acute angle closure glaucoma.
    ● Signs of blood pressure problems, such as dizziness, confusion, headache, chest pain, or shortness of breath.
    ● Swelling, pain, cramps, weakness, or ulcers in your legs.

    These are not all of the possible side effects of this medication. Call your health care provider if you have side effects that worsen or do not go away. You may also report side effects to FDA at 1-800-FDA-1088 or http://www.fda.gov/medwatch


  • Compounded Drug
    ● This prescription was specifically compounded in our pharmacy for you at the direction of your prescriber.
    ● Compounded medications are not FDA-approved but include active ingredients sourced from FDA registered facilities.
    ● If you notice any changes in its appearance, color, or consistency, please contact us or your prescriber immediately before using the medication.
    ● For any questions about this compounded medication, ask your health care provider or pharmacist. We prioritize the quality and safety of compounded medications and are available to address your concerns.

    Active ingredients
    Finasteride (pronounced fuh-na-str-ide) is used to help reduce hair loss and support hair growth.
    Minoxidil (pronounced muh-naak-suh-dil) is used to stimulate blood flow to hair follicles and promote hair regrowth.

    What to know before taking this medication
    Do not use this medication if you:
    ● Are or suspect you may be allergic to any of the ingredients in this compounded product.
    ● Are pregnant or suspect you may be pregnant.

    Things to know before taking this medication:
    ● Finasteride may affect prostate specific antigen (PSA) lab results. If you are planning to get a PSA test, please discuss with your health care provider that you are using finasteride.

    Use in pregnancy:
    ● Do not use during pregnancy or breastfeeding. There is a high risk this medication may cause fetal harm.
    ● Tell your health care provider if you are pregnant, plan on getting pregnant, or if you are breastfeeding.

    Prevent unintentional exposure to topical product:
    Unintentional exposure of this topical product to others can be dangerous, especially to children and pregnant women. Prevent this by taking the following precautions:
    ● Wash hands immediately after application.
    ● Avoid contact with unwashed or unclothed application sites in person’s using this topical product.
    ● Before skin-to-skin contact, wash area where topical product was applied.
    ● If exposure occurs, cleanse the skin with soap and water.

    Interactions with this medication:
    There are products that may interact with your medication that can change its effectiveness and increase the risk for serious side effects. It is important to keep a list of all products you currently use and talk to your health care provider before adding anything new to avoid potential interactions. Before starting this medication, talk to your health care provider for more details about how this medicine might interact with other products.

    What to know while taking this medication
    Serious side effects:
    Stop taking this medication and talk to your health care provider or seek medical attention right away if you develop:
    ● Signs of a severe, life-threatening allergic reaction such as:
    ● Swelling of the mouth, throat, tongue, eyes, hands and/or feet.
    ● Difficulty breathing or swallowing.
    ● Itchy skin or raised, red skin rash.

    Common side effects:
    The most common side effects in adults include:
    ● Skin redness, or dryness at site of application.
    ● Irritation at site of application
    ● Initial hair shedding.
    ● Hair texture changes.

    These are not all the possible side effects of this medication. Call your health care provider if you have side effects that worsen or do not go away. You may also report side effects to FDA at 1-800-FDA-1088 or http://www.fda.gov/medwatch

    How to use this medication
    How much do I use?
    ● Use this medication exactly as prescribed. Your health care provider will tell you how often to use this medication.

    How do I use this medication?
    ● Topical use : Wash your hands with warm water and soap before and after application. This medication is for use on the skin only. Do not get it in your eyes, nose, mouth, or other mucous membranes. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water. Use as directed by your health care provider.

    What if I miss a dose?
    ● If you missed a dose, use it as soon as you remember and use your next dose at your regularly scheduled time.
    ● If it is almost time for your next dose, skip the missed dose and use your next dose as scheduled. Do not use double of your prescribed dose.

    What if I take too much (overdose)?
    ● If you think you may have taken more than the prescribed dose of this medicine, call the poison control helpline at 1-800-222-1222 or seek medical care right away.

    How to store / dispose this medication
    How do I store this medication?
    ● Store at room temperature in a cool, dry place away from heat and direct sunlight.
    ● This product is flammable. Keep away from open flames, sparks, smoking or any source of ignition.
    ● Keep all drugs in a safe place and away from children and pets.

    How do I dispose of this medication?
    ● Do not throw away unused or expired drugs.
    ● Do not flush down the toilet or pour down the drain unless you are told to do so by your health care provider.
    ● Check with your pharmacist if you have questions on the best way to throw away your medication. There may be take-back programs in your area.
    ● Hazardous – dispose of properly.

    Caution: Hazardous Drug
    ● This medication includes components classified as hazardous drugs, which may cause adverse health effects if not used as directed by your prescriber.
    ● It is important to follow the directions given to you by your prescriber and practice safe handling procedures to ensure safe usage.

    Consumer Information Use and Disclaimer
    ● This medicine was prescribed for your condition. This product is only to be used by the person for whom it was prescribed. Do not use it for another condition or give the medicine to others.
    ● This document provides a summary of information about your medication and does not contain all possible information about this medication. This information does not endorse any treatments or medications as safe, effective or approved for treating a specific patient. It does not provide specific medical advice or replace guidance from your health care provider or pharmacist who prescribed or prepared the medication.
    ● If you have any questions or concerns, or want more information about your medication, talk to your health care provider or pharmacist.

    Pharmacy Information Curexa Pharmacy East 3007 Ocean Heights Ave Egg Harbor Township, NJ, 08234 Curexa Pharmacy East II 236 E. Jimmie Leeds Road Galloway, NJ, 08205 Curexa Pharmacy West 1343 N Colorado St, Suite 109 Gilbert, AZ, 85233 Phone: 855-927-0390 http://www.curexa.com


  • Compounded Drug
    ● This prescription was specifically compounded in our pharmacy for you at the direction of your prescriber.
    ● Compounded medications are not FDA-approved but include active ingredients sourced from FDA registered facilities.
    ● If you notice any changes in its appearance, color, or consistency, please contact us or your prescriber immediately before using the medication.
    ● For any questions about this compounded medication, ask your health care provider or pharmacist. We prioritize the quality and safety of compounded medications and are available to address your concerns.

    Active Ingredients
    Your compounded product may contain one or more of the following ingredients:
    Azelaic Acid (pronounced ay-zuh-lay-ik as-id) is used to help clear pores of bacteria, reduce inflammation caused by acne and rosacea while evening out skin tone.
    Clindamycin (pronounced klin-da-mye-sin) is used to help slow and stop the growth of bacteria on the skin and control acne.
    Dapsone (pronounced dap-sown) is used to help stop the growth of bacteria on the skin and reduce inflammation.
    Ivermectin (pronounced ai-vr-mek-tn) used to help reduce facial redness and inflammation caused by rosacea.
    Niacinamide (pronounced nye-a-sin-a-mide) is a form of vitamin B3 used to help with skin brightening and smooth your overall skin texture.
    Oxymetazoline (pronounced ak-see-meh-tuh- zow-leen) is used to narrow blood vessels under the skin to reduce facial redness caused by rosacea.
    Tretinoin (pronounced truh-ti-now-in) is a retinoid used to help reduce the appearance of wrinkles, fine lines and oil production.

    Before using this medication, talk to your health care provider if you:
    ● Have high sensitivity to the sun or spend a lot of time in the sun.
    ● Have eczema, as this product may cause irritation.
    ● Have a glucose-6-phosphate dehydrogenase deficiency (G6PD).
    ● Have higher than normal levels of methemoglobin in your blood (methemoglobinemia).
    ● Have a history of heart disease or blood pressure problems. heart attack, stroke, and/or blood vessel or blood flow problems.
    ● Have a history of Raynaud’s syndrome, Buerge disease, or Sjogren’s syndrome.

    Use in pregnancy:
    ● Do not use this medication if you are pregnant or breastfeeding and your medication contains Tretinoin, Dapsone, Oxymetazoline, and/or Ivermectin.
    ● Tell your health care provider if you are pregnant, plan on getting pregnant, or if you are breastfeeding.

    Use in children and adolescents:
    ● Do not use in children under 12 years of age.

    Interactions with this medication:
    There are products that may interact with your medication that can change its effectiveness and increase the risk for serious side effects. Before starting this medication, talk to your health care provider for more details about how this medicine might interact with other products and if you’re using any of these products:
    ● Other topical medications or OTC products.
    ● Medicated, abrasive or drying soaps, cleansers and cosmetics.
    ● Oral dapsone.

    This is not a complete list of possible interactions. It is important to keep a list of all products you currently use and talk to your health care provider before adding anything new to avoid potential interactions. Ask your health care provider or pharmacist for more details about how this medicine might interact with other products.

    What to know while using this medication
    Common side effects:
    The most common side effects in adults include:
    ● Increased sun sensitivity.
    ● Skin irritation, redness, or blisters at the site of application.
    ● Skin dryness, itching, and peeling.

    Serious side effects:
    Stop using this medication and talk to your health care provider or seek medical attention right away if you develop:
    ● Signs of a severe allergic reaction such as:
    ● Swelling of the mouth, throat, and/or tongue.
    ● Swelling of the eyes.
    ● Swelling of the hands and/or feet.
    ● Difficulty breathing or swallowing.
    ● Itchy skin.
    ● Raised, red skin rash.
    ● Diarrhea or bloody diarrhea.
    ● Colitis, or inflammation of the colon.
    ● Signs of hemolytic anemia, a breakdown of red blood cells, such as:
    ● Back pain, fever, and/or shortness of breath.
    ● Dark brown urine.
    ● Yellow or pale skin.
    ● Tiredness or weakness.
    ● Signs of methemoglobinemia such as:
    ● Grey or blue lips, nail beds, or inside of your mouth.
    ● Worsening rosacea.
    ● Acute angle closure glaucoma.
    ● Signs of blood pressure problems, such as dizziness, confusion, headache, chest pain, or shortness of breath.
    ● Swelling, pain, cramps, weakness, or ulcers in your legs.

    These are not all of the possible side effects of this medication. Call your health care provider if you have side effects that worsen or do not go away. You may also report side effects to FDA at 1-800-FDA-1088 or http://www.fda.gov/medwatch

    How to use this medication
    How much do I use?
    ● Use the medication exactly as prescribed. Your health care provider will tell you how often to use this medication.

Gentle Exfoliating Daily Cleanser

This hydrating, sulfate and paraben-free cleanser removes makeup, oil, and impurities and gently exfoliates dead skin cells, while the cream base prevents moisture evaporation from the skin’s surface resulting in a smooth, radiant complexion.


Hydrate, Exfoliate, Radiate — All in One Step

Instant Glow

See a smoother, brighter complexion after the first wash.

Dermatologist-Crafted

Backed by science, safe for daily use.

Clean Formula

Sulfate-free, paraben-free, cruelty-free.

Cleanse & Exfoliate

Removes impurities while gently renewing skin.

  • Water/Aqua/Eau, Glycolic Acid, Cetyl Alcohol, Sorbitol, Sodium Hydroxide, Steareth-21, Butylene Glycol, Phenoxyethanol, Potassium Cetyl Phosphate, Xanthan Gum, Ethylhexylglycerin, Palmitic Acid, Panthenol (Pro-vitamin B5), Disodium EDTA Glycolic Acid 10.0%, Sorbitol, Panthenol (Pro-vitamin B5)

  • It contains Glycolic Acid 10% to remove dead skin cells from the skin’s surface effectively and helps prevent moisture loss from the skin’s surface, resulting in a more radiant complexion.

  • Apply cleanser over dry skin, avoiding eye area. To remove, rinse with warm water and pat dry. Can be used twice daily or as otherwise directed.
    Glycolic Acid 10%, Pro-vitamin B5, Sorbitol

Dewy Daily Moisturizer

This lightweight, oil-free moisturizer effectively hydrates the skin without adding oil or shine, creating visibly radiant and clear skin. In addition, robust, naturally soothing antioxidants protect the skin, and ceramides prevent dryness and irritation while reducing the appearance of redness. Niacinamide reduces the appearance of enlarged pores and improves the skin’s texture.


Silky Smooth. Soft Glow. All Day Comfort.

Brighter Skin Daily

Glycolic acid smooths texture and boosts radiance.

Hydration That Lasts

Cream base prevents dryness after cleansing.

Safe for Sensitive Skin

Sulfate-free, paraben-free, dermatologist-approved.

Hydration + Exfoliation in One Step

Cream base locks in moisture for a soft, radiant finish.

  • Ingredients:

    Niacinamide (Vitamin B3), Saccharide Isomerate, Euterpe Oleracea (Acai) Fruit Extract, Salix Alba (Willow) Bark Extract, Aloe Barbadensis Leaf Extract, Camellia Sinensis (Green Tea) Leaf Extract, Ceramide NP, Phytosphingosine, Ceramide AP, Ceramide

    EOP Ingredients:

    Water/Aqua/Eau, Ethylhexyl Stearate, Glycerin, Niacinamide (Vitamin B3), Cetearyl Alcohol, Sodium Acrylates Copolymer, Saccharide Isomerate, Glyceryl Stearate, PEG-100 Stearate, Euterpe Oleracea (Acai) Fruit Extract, Lecithin, Sodium PCA, Salix Alba (Willow) Bark Extract, Aloe Barbadensis Leaf Extract, Camellia Sinensis(Green Tea) Leaf Extract, Sodium Lauroyl Lactylate, Ceramide NP, Phyto- sphingosine, Ceramide AP, Cholesterol, Xanthan Gum, Carbomer, Ceramide EOP, Ethylhexylglycerin, Phenoxyethanol

  • It is a lightweight, oil-free, and fragrance-free formula that effectively replenishes and hydrates the skin. It has 3 ceramides that hydrate, replenish and restore the skin by mimicking the skin’s own natural moisturization.

  • Apply a generous amount to the face, avoiding eye area. Allow to absorb before applying additional product. Use twice daily or as otherwise directed.

Clear Defense Daily Sunscreen

The Clear Defense sunblock contains an innovative blend of active ingredients, including non-nano zinc oxide, the most comprehensive physical sunblock available, and Knotweed extract, which has been shown to prevent damage from infrared radiation. This fast-absorbing SPF also features a high level of Niacinamide to promote a smoother, clearer complexion.


Advanced Formula That Shields Your Skin from Morning to Night

Dermatologist-Crafted

Medical-grade sunscreen crafted for professional-level protection.

Long-Lasting Defense

Advanced UV filters keep working when ordinary sunscreens wear off.

Skin-Perfecting Care

Niacinamide reduces redness and evens tone while you protect.

Clear, Lightweight Finish

No white cast, no greasy residue. Just smooth, protected skin.

  • Ingredients:

    Zinc Oxide 12.0%, Octinoxate 7.5% INGREDIENT HIGHLIGHTS Niacinamide (Vitamin B3), Tocopheryl Acetate (Vitamin E), Polygonum Aviculare Extract (Knotweed Extract), Sodium Hyaluronate (Hyaluronic Acid)

    Inactive Ingredients:

    Water, Cyclopentasiloxane, Niacinamide (Vitamin B3), Oleth-3 Phosphate, Octyldodecyl Neopentanoate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, PEG-7 Trimethylolpro- pane Coconut Ether, Glycerin, Tocopheryl Acetate (Vitamin E), Polygonum Aviculare (Knotweed) Extract, Sodium Hyaluronate (Hyaluronic Acid), Disodium EDTA, Sodium Hydroxide, Citric Acid, Phenoxyethanol, Ethylhexyl- glycerin, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Triethoxysi- lylethyl Polydimethylsiloxyethyl Hexyl Dimethicone, Triethoxycaprylylsilane

  • For this sunscreen, recommended skin types include acne, combo, oily. This fast-absorbing SPF also features a high level of Niacinamide to promote a smoother, clearer complexion.

  • Apply to face & neck, avoiding the eye area. Wait at least 15 minutes before sun exposure, or as directed by a physician. Reapply after prolonged exposure, physical activity, perspiration or contact with water.