Acne Care delivers prescription-strength Clindamycin, Niacinamide, and Tretinoin. Compounded by a licensed pharmacy based on a provider's prescription.
No appointment required.


Most OTC products aren't equipped to treat it. Acne Care by DoctorDerm delivers prescription-strength actives that work at the source: regulating sebum, targeting bacteria, and accelerating cell turnover. The stuff that requires a real provider to prescribe, because it's actually strong enough to work.
Tens of millions of Americans deal with acne every year, and most still rely on over-the-counter products that aren't equipped to treat a medical condition. That's why we built DoctorDerm: prescription-strength treatment, prescribed by a real provider, without the waiting room.
of people between the ages of 12 and 24 experience at least minor acne.
American Academy of Dermatologyof adult women still deal with acne. Adult acne continues to rise, and it doesn't always grow out of you.
American Academy of Dermatology
A real provider reviews your case and prescribes online. Four simple steps, no appointments.
Take a quick skin assessment. Upload a few photos. No appointments, no waiting rooms.
A licensed medical provider reviews your assessment and photos and decides if treatment is appropriate.
Your prescription treatment ships to your door every 60 days.
Adjust, check in, and get ongoing support whenever you need it.
Three prescription-grade actives. Each one doing something the others can't.
C₁₈H₃₄ClN₂O₈PS · AntibioticClindamycin Phosphate is a topical prescription antibiotic that works by binding to bacterial ribosomes and blocking protein synthesis in Cutibacterium acnes, the primary bacteria responsible for acne. By reducing bacterial colonization in the follicle, it helps address the infection and inflammatory cascade that causes papules, pustules, and cystic breakouts.
C₆H₆N₂O · Vitamin B3Niacinamide is a water-soluble form of Vitamin B3 designed to support acne-prone skin across multiple pathways. It strengthens the skin's lipid barrier by stimulating ceramide production, helps regulate sebum, and acts as an anti-inflammatory to calm the redness and irritation that accompany active breakouts.
C₂₀H₂₈O₂ · RetinoidTretinoin is a first-generation retinoic acid widely used in prescription acne treatment. It accelerates the natural cell turnover cycle, pushing dead cells out of the follicle before they can combine with sebum and bacteria to form a blockage. This comedolytic action may help reduce the formation of blackheads and whiteheads.
Individual results may vary.
Apply a small amount to clean, dry skin as directed. Your provider includes specific instructions with your prescription.
Three months in and my skin texture has improved more than it did from years of random drugstore products. Worth every penny.
I have been using Acne Care for a few months and am seeing a big improvement! My acne is finally getting better!! Wish I had known about this sooner.
Starting DoctorDerm is the best skin decision I've made. The improvement in my texture and tone has made me so much more confident going makeup-free.
I have been using DoctorDerm for two months and have seen a big improvement in the area I am targeting. And the process was so much easier than going to my dermatologist.
Three months in and my skin texture has improved more than it did from years of random drugstore products. Worth every penny.
I have been using Acne Care for a few months and am seeing a big improvement! My acne is finally getting better!! Wish I had known about this sooner.
Starting DoctorDerm is the best skin decision I've made. The improvement in my texture and tone has made me so much more confident going makeup-free.
I have been using DoctorDerm for two months and have seen a big improvement in the area I am targeting. And the process was so much easier than going to my dermatologist.
This prescription-strength product works for me while others I tried did not.
DoctorDerm providers combine real clinical expertise with a genuine interest in patient well-being. Finally getting the care I deserve.
This slots right into my routine between my retinoid and moisturizer. My skin feels plumper and the dullness I used to see in the morning is gone.
This prescription-strength product works for me while others I tried did not.
DoctorDerm providers combine real clinical expertise with a genuine interest in patient well-being. Finally getting the care I deserve.
This slots right into my routine between my retinoid and moisturizer. My skin feels plumper and the dullness I used to see in the morning is gone.
Individual results may vary. Testimonials reflect personal experiences and do not guarantee outcomes.
Stronger than anything available over the counter. Because acne is a medical condition, not a skincare problem.
Targets bacteria and inflammation at the source to help existing pimples clear faster.
Designed to help keep pores clear and optimize skin cell turnover to reduce breakouts.
Tretinoin accelerates cell renewal, helping to reduce the appearance of dark spots and uneven texture left behind by past breakouts.
A licensed provider reviews your case and writes your prescription, entirely online.
Individual results may vary.
| Feature | DoctorDerm | Other Online Clinics | In-Office Care |
|---|---|---|---|
| Prescription-grade formula | ✓ | ✓ | ✓ |
| Real provider reviews your case | ✓ | ✕ | ✓ |
| Ongoing provider support | ✓ | ✕ | ✕ |
| No waiting room | ✓ | ✓ | ✕ |
| Ships to your door | ✓ | ✓ | ✕ |
This comparison is based on publicly available information as of 2026. We encourage you to do your own research. We're just pretty confident you'll end up here anyway.
Prescription-grade formula · Provider-prescribed · Free shipping · Ongoing care
Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.