Anti-Aging Care delivers a prescription-strength combination of Tretinoin, Azelaic Acid, and Niacinamide. Compounded by a licensed pharmacy based on a provider's prescription.
No appointment required.

Fine lines, uneven tone, and loss of firmness aren't inevitable. They're the result of slowing cell turnover and collagen production. Anti-Aging Care by DoctorDerm uses a prescription-strength combination of Tretinoin, Azelaic Acid, and Niacinamide to address wrinkles, not just the surface appearance.
Drugstore retinols don't deliver the actives or the strengths needed to actually change skin. That's why we built DoctorDerm: prescription-strength Tretinoin, prescribed by a real provider, without the waiting room.
more potent than over-the-counter retinol. Tretinoin acts directly without the multi-step skin conversion retinol requires.
Clinical Interventions in Aging, 2006showed statistically significant improvement in fine wrinkles (P<0.001) in a 2025 systematic review of prescription tretinoin trials.
Dermatology Practical & Conceptual, 2025
A real provider reviews your case and prescribes online. Four simple steps, no appointments.
Take a quick skin assessment. Upload a few photos. No appointments, no waiting rooms.
A licensed medical provider reviews your assessment and photos and decides if treatment is appropriate.
Your prescription treatment ships to your door every 60 days.
Adjust, check in, and get ongoing support whenever you need it.
Three prescription-grade actives. Each one doing something the others can't.
C₉H₁₆O₄ · Dicarboxylic AcidAzelaic Acid is a naturally occurring dicarboxylic acid with multiple mechanisms that make it valuable in anti-aging treatment. It inhibits tyrosinase, helping reduce melanin overproduction, exerts anti-inflammatory effects that help calm irritation associated with retinoid use, and gently promotes cell turnover to help improve surface texture.
C₆H₆N₂O · Vitamin B3Niacinamide is a water-soluble form of Vitamin B3 that works across multiple pathways to support aging skin. It helps strengthen the skin's lipid barrier, may help reduce the appearance of discoloration and age spots over time, and supports maintaining an even, refined skin surface.
C₂₀H₂₈O₂ · RetinoidTretinoin is the gold standard prescription retinoid for anti-aging. It binds to retinoic acid receptors in skin cells, accelerating the natural cell turnover cycle and supporting collagen synthesis. This may help reduce the appearance of fine lines, support improved skin firmness, and help create a more refined surface texture over time.
Individual results may vary.
Apply a small amount to clean, dry skin as directed. Your provider includes specific instructions with your prescription.
I have been using Anti-Aging Care for a few months and am seeing a big improvement! I am seeing a reduction in the appearance of wrinkles! Wish I had known about this a lot sooner.
I was skeptical at first, but my fine lines have genuinely softened. People keep asking what I'm doing differently. The answer is DoctorDerm.
Starting DoctorDerm is the best skin decision I've made. The improvement in my texture and tone has made me so much more confident going makeup-free.
Three months in and my skin texture has improved more than it did from years of random drugstore products. Worth every penny.
I have been using Anti-Aging Care for a few months and am seeing a big improvement! I am seeing a reduction in the appearance of wrinkles! Wish I had known about this a lot sooner.
I was skeptical at first, but my fine lines have genuinely softened. People keep asking what I'm doing differently. The answer is DoctorDerm.
Starting DoctorDerm is the best skin decision I've made. The improvement in my texture and tone has made me so much more confident going makeup-free.
Three months in and my skin texture has improved more than it did from years of random drugstore products. Worth every penny.
This prescription-strength product works for me while others I tried did not.
DoctorDerm providers combine real clinical expertise with a genuine interest in patient well-being. Finally getting the care I deserve.
This slots right into my routine between my retinoid and moisturizer. My skin feels plumper and the dullness I used to see in the morning is gone.
This prescription-strength product works for me while others I tried did not.
DoctorDerm providers combine real clinical expertise with a genuine interest in patient well-being. Finally getting the care I deserve.
This slots right into my routine between my retinoid and moisturizer. My skin feels plumper and the dullness I used to see in the morning is gone.
Individual results may vary. Testimonials reflect personal experiences and do not guarantee outcomes.
Prescription-strength Tretinoin helps support collagen production and cell turnover, which helps reduce the appearance of fine lines with consistent use.
May help support the appearance of firmer, more refined skin at the cellular level with consistent use.
May help reduce the appearance of rough patches and uneven tone for a smoother-looking surface with consistent use over time.
Azelaic Acid may help reduce the appearance of dullness and address the appearance of hyperpigmentation, supporting a more even complexion over time.
Niacinamide is formulated to help support the skin's lipid barrier, which may help reduce sensitivity and water loss over time.
Individual results may vary.
| Feature | DoctorDerm | Other Online Clinics | In-Office Care |
|---|---|---|---|
| Prescription-grade formula | ✓ | ✓ | ✓ |
| Real provider reviews your case | ✓ | ✕ | ✓ |
| Ongoing provider support | ✓ | ✕ | ✕ |
| No waiting room | ✓ | ✓ | ✕ |
| Ships to your door | ✓ | ✓ | ✕ |
This comparison is based on publicly available information as of 2026. We encourage you to do your own research. We're just pretty confident you'll end up here anyway.
Prescription-grade formula · Provider-prescribed · Free shipping · Ongoing care
Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.