I have been using Anti-Aging Care for a few months and am seeing a big improvement! I am seeing a reduction in the appearance of wrinkles! Wish I had known about this a lot sooner.
Anti-Aging Care delivers a prescription-strength combination of Tretinoin, Azelaic Acid, and Niacinamide. Compounded by a licensed pharmacy based on a provider's prescription.
No appointment required.
Fine lines, uneven tone, and loss of firmness aren't inevitable. They're the result of slowing cell turnover and collagen production. Anti-Aging Care by DoctorDerm uses a prescription-strength combination of Tretinoin, Azelaic Acid, and Niacinamide to address wrinkles, not just the surface appearance.
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Drugstore retinols don't deliver the actives or the strengths needed to actually change skin. That's why we built DoctorDerm: prescription-strength Tretinoin, prescribed by a real provider, without the waiting room.
more potent than over-the-counter retinol. Tretinoin acts directly without the multi-step skin conversion retinol requires.
showed statistically significant improvement in fine wrinkles (P<0.001) in a 2025 systematic review of prescription tretinoin trials.
Take a quick skin assessment. Upload a few photos. No appointments, no waiting rooms.
A licensed medical provider reviews your assessment and photos and decides if treatment is appropriate.
Your prescription treatment ships to your door every 60 days.
Adjust, check in, and get ongoing support whenever you need it.
Three prescription-grade actives. Each one doing something the others can't.
C₉H₁₆O₄ · Dicarboxylic AcidBrightens and evens
Azelaic Acid is a naturally occurring dicarboxylic acid with multiple mechanisms that make it valuable in anti-aging treatment. It inhibits tyrosinase, helping reduce melanin overproduction, exerts anti-inflammatory effects that help calm irritation associated with retinoid use, and gently promotes cell turnover to help improve surface texture.
C₆H₆N₂O · Vitamin B3Firms and smooths
Niacinamide is a water-soluble form of Vitamin B3 that works across multiple pathways to support aging skin. It helps strengthen the skin's lipid barrier, may help reduce the appearance of discoloration and age spots over time, and supports maintaining an even, refined skin surface.
C₂₀H₂₈O₂ · RetinoidSupports cellular renewal
Tretinoin is the gold standard prescription retinoid for anti-aging. It binds to retinoic acid receptors in skin cells, accelerating the natural cell turnover cycle and supporting collagen synthesis. This may help reduce the appearance of fine lines, support improved skin firmness, and help create a more refined surface texture over time.
Individual results may vary.

Apply a small amount to clean, dry skin as directed. Your provider includes specific instructions with your prescription.
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I have been using Anti-Aging Care for a few months and am seeing a big improvement! I am seeing a reduction in the appearance of wrinkles! Wish I had known about this a lot sooner.
Verified Customer
This prescription-strength product works for me while others I tried did not.
Verified Customer
Individual results may vary. Testimonials reflect personal experiences and do not guarantee outcomes.
Prescription-strength Tretinoin helps support collagen production and cell turnover, which helps reduce the appearance of fine lines with consistent use.
May help support the appearance of firmer, more refined skin at the cellular level with consistent use.
May help reduce the appearance of rough patches and uneven tone for a smoother-looking surface with consistent use over time.
Azelaic Acid may help reduce the appearance of dullness and address the appearance of hyperpigmentation, supporting a more even complexion over time.
Niacinamide is formulated to help support the skin's lipid barrier, which may help reduce sensitivity and water loss over time.

Individual results may vary.
This comparison is based on publicly available information as of 2026. We encourage you to do your own research. We're just pretty confident you'll end up here anyway.
Yes. DoctorDerm is a real telehealth service. Your assessment and photos are reviewed by a Licensed Medical Provider who decides if prescription treatment is appropriate. Your prescription is filled by a licensed compounding pharmacy and shipped to your door.
Take a short online skin assessment and upload a few photos. A Licensed Medical Provider reviews your case and decides if treatment is appropriate. If prescribed, your prescription is filled by a licensed pharmacy and ships to your door every 60 days. You can message your provider through the portal anytime.
Anti-Aging Care is a prescription-grade product reviewed and prescribed by a Licensed Medical Provider. Tretinoin has been prescribed by dermatologists for over 50 years and is one of the most studied actives in skincare. Your provider reviews your medical history to decide if treatment is appropriate.
Results vary from person to person. Some patients begin to notice changes in skin texture and tone within a few weeks, while others see more gradual improvement over time. Consistent, long-term use is the most important factor.
Many people with sensitive skin can use this treatment. Your provider will review your skin concerns to determine appropriate concentrations, and may recommend easing in gradually to minimize irritation.
Yes. All DoctorDerm formulas are prescription-grade and require a provider consultation. Your assessment is the first step.
Tretinoin is not recommended during pregnancy. If you are pregnant or planning to become pregnant, please inform your provider during your assessment.
Your provider will advise on what to use alongside your formula. Generally, a gentle cleanser, moisturizer, and daily SPF are recommended. Avoid combining with other strong actives unless your provider advises otherwise.
Tretinoin is prescription-strength retinoic acid, significantly more potent than over-the-counter retinol. Retinol must be converted by the skin before it can work; Tretinoin is already in its active form and works more directly and effectively.
DoctorDerm treatments combine multiple prescription actives into a single formula that you typically wouldn't receive as one prescription in a traditional dermatology office. Our treatments are prepared and delivered directly to your door, giving you a complete skincare experience without the wait times or in-office visits.
$44.50/month
Billed as $89 every 2 months
Start my assessmentPrescription-grade formula · Provider-prescribed · Free shipping · Ongoing care