1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas
1,000+ happy customers

Acne Care

Help achieve clearer skin with clinically-studied ingredients.

Clindamycin Phosphate / Niacinamide / Tretinoin

$44.50/month

Billed as $89 every 2 months

Start My Assessment
Prescription-grade formula Provider-prescribed Ships to your door
Before Before
After After
Clinician Recommended
Acne Care prescription formula bottle
Prescription-grade formula Provider-prescribed Ships to your door

Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.

About This Formula

Acne isn't a skincare routine you haven't found yet. It's a medical condition.

Most OTC products aren't equipped to treat it. Acne Care by DoctorDerm delivers prescription-strength actives that work at the source: regulating sebum, targeting bacteria, and accelerating cell turnover. The stuff that requires a real provider to prescribe, because it's actually strong enough to work.

Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.

Acne Care contains Clindamycin Phosphate, Niacinamide, and Tretinoin: three prescription-grade actives compounded into a single formula by a licensed pharmacy based on your provider's prescription.

Apply a small amount to clean, dry skin as directed. Your provider will include specific application instructions with your prescription.

Complete a short skin assessment and upload a few photos. A licensed provider personally reviews your case and builds your treatment plan. If prescribed, your formula ships straight to your door.

Most patients may begin to notice changes with consistent use. Individual results vary., though results vary. Individual response depends on skin type, condition severity, and consistent use.

Woman with clear, healthy skin

Clinically-Studied Ingredients

Start My Assessment

The Formula

What's In It

Three prescription-grade actives. Each one doing something the others can't.

Clindamycin Phosphate

C₁₈H₃₄ClN₂O₈PS  ·  Antibiotic

Clindamycin Phosphate is a topical prescription antibiotic that works by binding to bacterial ribosomes and blocking protein synthesis in Cutibacterium acnes, the primary bacteria responsible for acne. By reducing bacterial colonization in the follicle, it helps address the infection and inflammatory cascade that causes papules, pustules, and cystic breakouts. It also decreases the production of bacterial lipases, which break down sebum into free fatty acids that further irritate pore linings. Many patients notice a reduction in active inflammation within the first few weeks of consistent use.

Acne Care formula bottle

Niacinamide

C₆H₆N₂O  ·  Vitamin B3

Niacinamide is a water-soluble form of Vitamin B3 designed to support acne-prone skin across multiple pathways. It inhibits the transfer of melanosomes to keratinocytes, which may help reduce post-acne discoloration over time. It strengthens the skin's lipid barrier by stimulating ceramide production, reducing transepidermal water loss and helping skin become more resilient to environmental stressors. Niacinamide also helps regulate sebum production and may help reduce pore appearance by improving elasticity around the pore lining. As an anti-inflammatory, it helps calm the redness and irritation that accompany active breakouts, making it an ideal supportive ingredient alongside stronger actives like Clindamycin and Tretinoin.

Tretinoin

C₂₀H₂₈O₂  ·  Retinoid

Tretinoin is a first-generation retinoic acid widely used in prescription acne treatment. It works by binding to retinoic acid receptors in skin cells, which accelerates the natural cell turnover cycle, pushing dead cells out of the follicle before they can combine with sebum and bacteria to form a blockage. This comedolytic action may help reduce the formation of blackheads and whiteheads. Tretinoin also normalizes abnormal keratinization within the follicle, designed to help address acne at the structural level. Over time, continued use may help improve overall skin texture, reduce the appearance of acne scarring, and create a more even, refined skin surface. Because it increases cellular activity, some patients experience an initial purging phase in the first 2–4 weeks before seeing improvement.

Acne Care formula texture

This information is for educational purposes only and is not a substitute for medical advice. Please consult your healthcare provider before starting or changing any medication.

Start My Assessment
Clear skin results from DoctorDerm

Benefits

Why People Choose Acne Care

  • 01

    Prescription-grade strength

    Stronger than anything available over the counter. Because acne is a medical condition, not a skincare problem.

  • 02

    Designed to help clear active breakouts

    Targets bacteria and inflammation at the source to help existing pimples clear faster.

  • 03

    Helps protect against new acne formation

    Designed to help keep pores clear and optimize skin cell turnover to reduce breakouts.

  • 04

    Helps reduce the appearance of post-acne marks

    Tretinoin accelerates cell renewal, helping to reduce the appearance of dark spots and uneven texture left behind by past breakouts.

  • 05

    No waiting room, ever

    A licensed provider reviews your case and writes your prescription, entirely online.

Start My Assessment

How It Works

Great skin shouldn't require a waiting room.

From your first question to your best skin. Here's how DoctorDerm works.

Step 1
01

Tell Us About Your Skin

Take a quick skin assessment. Upload a few photos. No appointments, no waiting rooms.

Step 2
02

A Real Provider Reviews Your Case

A provider personally reviews your results and builds your treatment plan. Made for your skin, no one else's.

Step 3
03

Your Prescription, Delivered

Your prescription treatment ships to your door every 60 days.

Step 4
04

Ongoing Care That Adapts

Adjust, check in, and get ongoing support whenever you need it.

Get Started

The Difference

Not all skincare is created equal.

See how DoctorDerm stacks up against the alternatives.

DoctorDerm Other Online Clinics In-Office Care
Prescription-grade formula
Real provider reviews your case
Personalized to your skinPartial
Ongoing provider support
No waiting room
Ships to your door

This comparison is based on publicly available information as of 2026. We encourage you to do your own research. We're just pretty confident you'll end up here anyway.

The only place you get real provider care, real prescriptions, and real ongoing support, without ever leaving home.

Start My Assessment

Reviews

What Patients Are Saying

"I have been using Acne Care for a few months and am seeing a big improvement! My acne is finally getting better!! Wish I had known about this sooner."

Verified Customer

"This prescription-strength product works for me while others I tried did not."

Verified Customer

Before treatment, acne-prone skin Before
After treatment, clear skin After

Rx-Grade

Prescription Formula

1,000+

Patients Treated

Licensed

Providers Only

Individual results may vary. Testimonials reflect personal experiences and do not guarantee outcomes.

Start My Assessment

FAQ

Frequently Asked Questions

Most patients may begin to see improvement with consistent use. Individual results vary as the skin adjusts to the formula. Individual results vary.

Yes, many people with sensitive skin are able to use this treatment. A licensed provider will review your skin concerns and medical history to determine if it's appropriate for you and may recommend starting gradually to help minimize irritation.

Yes. All DoctorDerm formulas are prescription-grade and require a provider consultation. Your assessment is the first step.

Tretinoin is not recommended during pregnancy. If you are pregnant or planning to become pregnant, ask your provider about our Prenatal Acne Care formula instead.

This treatment helps support management of different types of acne, including deeper or more stubborn breakouts. Your provider will review your skin concerns to determine if it's the right option for you.

This formula is prescribed for facial use. Mention any body acne concerns during your assessment.

Tretinoin is a vitamin A derivative that has been used in dermatology for decades. It's designed to help with acne when used under provider supervision at the appropriate concentration for your skin.

DoctorDerm treatments combine ingredients into customized formulas that you typically wouldn't receive as a single prescription in a traditional dermatology office. Our treatments are prepared and delivered directly to your door, giving you a complete skincare experience without the wait times or in-office visits.

Start My Assessment

Ready to start with Acne Care?

$44.50/month. Billed as $89 every 2 months

Prescription-grade formula Provider-prescribed Free shipping Ongoing care
Start My Assessment

Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.