1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas
1,000+ happy customers

Eczema Care

Prescription-strength relief for chronic flare-ups.

Contains Tacrolimus

$44.50/month

Billed as $89 every 2 months

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Prescription-grade formula Provider-prescribed Ships to your door
Clinician Recommended
Eczema Care prescription formula bottle
Prescription-grade formula Provider-prescribed Ships to your door

Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.

About This Formula

Most eczema creams treat the surface. This is designed to help address the source.

Over-the-counter moisturizers and hydrocortisone creams can temporarily relieve symptoms, but they don’t address the underlying immune dysregulation driving eczema. Eczema Care by DoctorDerm uses Tacrolimus, a prescription-strength immunomodulator, designed to help calm the immune response that contributes to chronic flare-ups, itching, and barrier breakdown.

Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.

Eczema Care is formulated with Tacrolimus, a prescription-grade topical immunomodulator compounded by a licensed pharmacy based on your provider’s prescription.

Apply a small amount to clean, dry skin as directed. Your provider will include specific application instructions with your prescription.

Complete a short skin assessment and upload a few photos. A licensed provider personally reviews your case and builds your treatment plan. If prescribed, your formula ships straight to your door.

Many patients may begin to notice reduced itching and inflammation with consistent use. Individual results vary. of consistent use.

Woman with clear, healthy skin

Clinically-Studied Ingredients

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The Formula

What's In It

Prescription-grade immunomodulation. Targeting the immune response behind eczema.

Tacrolimus

C₄₄H₆₉NO₁₂  ·  Immunomodulator

Tacrolimus is a macrolide calcineurin inhibitor that works by helping suppress T-cell activation, a key immune mechanism behind atopic eczema flares. Unlike topical corticosteroids, it does not cause skin atrophy with long-term use, making it suitable for sensitive areas including the face and body folds. It may help reduce the production of pro-inflammatory cytokines that contribute to the itch-scratch cycle and barrier breakdown characteristic of eczema. Tacrolimus is FDA-approved for moderate-to-severe atopic dermatitis and has been used in dermatology for decades with a well-established safety profile.

Eczema Care formula bottle

How It Works

Calcineurin Inhibition  ·  Mechanism

Tacrolimus works by binding to FK-binding protein 12 (FKBP12), forming a complex that may help inhibit calcineurin, a phosphatase important for T-cell activation. This helps interrupt the production of inflammatory cytokines including IL-2, IL-4, and TNF-alpha, which contribute to the atopic eczema inflammatory cascade. This mechanism is fundamentally different from steroids, which work by broadly suppressing the immune system. Tacrolimus is designed to target the specific immune pathway involved in eczema.

Clinical Profile

FDA-Approved  ·  Atopic Dermatitis

Tacrolimus has been FDA-approved for moderate-to-severe atopic dermatitis since 2000 and has a well-established long-term safety record. Unlike topical corticosteroids, it does not cause skin thinning, telangiectasia, or HPA-axis suppression with extended use. This makes it a valuable option for facial eczema and pediatric use where steroid-related side effects are a concern. It can be used continuously or intermittently as a maintenance treatment to help manage flare frequency over time.

Eczema Care formula texture

This information is for educational purposes only and is not a substitute for medical advice. Please consult your healthcare provider before starting or changing any medication.

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Eczema care results from DoctorDerm

Benefits

Why People Choose Eczema Care

  • 01

    Helps calm flare-ups at the source

    Tacrolimus is formulated to help calm the immune signals that contribute to eczema flares, not just mask the symptoms.

  • 02

    Helps reduce itching and inflammation

    Formulated to help address the inflammatory pathways associated with eczema-related itching, redness, and discomfort.

  • 03

    Supports long-term skin barrier repair

    With consistent use, helps restore the compromised skin barrier that makes eczema-prone skin vulnerable to triggers and irritants.

  • 04

    Steroid-free prescription option

    Tacrolimus offers an alternative to topical steroids, without the concerns associated with long-term steroid use.

  • 05

    No waiting room, ever

    A licensed provider reviews your case and writes your prescription, entirely online.

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How It Works

Great skin shouldn't require a waiting room.

From your first question to your best skin. Here's how DoctorDerm works.

Step 1
01

Tell Us About Your Skin

Take a quick skin assessment. Upload a few photos. No appointments, no waiting rooms.

Step 2
02

A Real Provider Reviews Your Case

A provider personally reviews your results and builds your treatment plan. Made for your skin, no one else's.

Step 3
03

Your Prescription, Delivered

Your prescription treatment ships to your door every 60 days.

Step 4
04

Ongoing Care That Adapts

Adjust, check in, and get ongoing support whenever you need it.

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The Difference

Not all skincare is created equal.

See how DoctorDerm stacks up against the alternatives.

DoctorDerm Other Online Clinics In-Office Care
Prescription-grade formula
Real provider reviews your case
Personalized to your skinPartial
Ongoing provider support
No waiting room
Ships to your door

This comparison is based on publicly available information as of 2026. We encourage you to do your own research. We're just pretty confident you'll end up here anyway.

The only place you get real provider care, real prescriptions, and real ongoing support, without ever leaving home.

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Reviews

What Patients Are Saying

"I have been using Eczema Care for months and I have seen improvement in my skin! I've noticed my eczema is better controlled. This was so easy, wish I had it before, definitely will keep buying."

Verified Customer

"I came across Eczema Care and after a few weeks of using it my skin already feels more plump, I’ve noticed improvement in my blemishes and discoloration, and I’ve gotten so many compliments at work!"

Verified Customer

"My dermatologist had a 3-month wait. DoctorDerm had me started in days. My eczema has barely flared since, this has worked better for me than anything I've tried before."

Verified Customer

Rx-Grade

Prescription Formula

1,000+

Patients Treated

Licensed

Providers Only

Individual results may vary. Testimonials reflect personal experiences and do not guarantee outcomes.

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FAQ

Frequently Asked Questions

Many patients may notice reduced itching and inflammation with consistent use. Individual results vary. of consistent use.

Yes. Tacrolimus is specifically formulated for sensitive, eczema-prone skin and is frequently used on the face and in skin folds where steroids are not recommended.

Yes. All DoctorDerm formulas are prescription-grade and require a provider consultation. Your assessment is the first step.

Tacrolimus 0.03% is FDA-approved for use in children 2 years and older. Your provider will determine the appropriate concentration and confirm suitability based on your child’s age and history.

No. Tacrolimus is a calcineurin inhibitor, not a corticosteroid. It provides effective eczema control without the skin-thinning effects associated with long-term steroid use.

Yes. Tacrolimus is one of the few prescription eczema treatments safe for use on the face and sensitive areas where steroids are typically avoided.

Tacrolimus is suitable for long-term maintenance use. Your provider will advise on the best approach, whether continuous use or intermittent therapy to reduce flare frequency.

DoctorDerm treatments combine ingredients into customized formulas that you typically wouldn’t receive as a single prescription in a traditional dermatology office. Our treatments are prepared and delivered directly to your door, giving you a complete skincare experience without the wait times or in-office visits.

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Ready to start with Eczema Care?

$44.50/month. Billed as $89 every 2 months

Prescription-grade formula Provider-prescribed Free shipping Ongoing care
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Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.