1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas 1,000+ patients treated Licensed providers only Ships to your door Prescription-grade formulas
1,000+ happy customers

Hair Removal Cream

Designed to help slow unwanted facial hair growth with a prescription formula.

Eflornithine HCl Monohydrate

$44.50/month

Billed as $89 every 2 months

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Prescription-grade formula Provider-prescribed Ships to your door
Clinician Recommended
Hair Removal Cream prescription formula bottle
Prescription-grade formula Provider-prescribed Ships to your door

Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.

About This Formula

Designed to help reduce waxing and shaving frequency for smoother skin.

Shaving, waxing, and threading treat the surface. Hair Removal Cream by DoctorDerm is designed to work differently. Eflornithine HCl is a prescription ingredient formulated to help slow hair regrowth at the follicle level, which may reduce the rate and thickness of new growth over time. May help reduce treatment frequency and maintenance needs.

Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.

Hair Removal Cream is formulated with Eflornithine HCl Monohydrate, a prescription-grade active designed to help inhibit an enzyme involved in hair growth, compounded by a licensed pharmacy based on your provider’s prescription.

Apply a small amount to clean, dry skin as directed. Your provider will include specific application instructions with your prescription.

Complete a short skin assessment and upload a few photos. A licensed provider personally reviews your case and builds your treatment plan. If prescribed, your formula ships straight to your door.

Most patients may notice slower regrowth within 4 to 8 weeks of consistent use, though results vary. It is designed to work best when used alongside your current hair removal method.

Woman with clear, healthy skin

Clinically-Studied Ingredients

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The Formula

What's In It

Prescription-strength formula designed to help with regrowth management. Contains the active ingredient found in the only FDA-approved topical for facial hair.

Eflornithine HCl

C₆H₁₂FN₂O₂·HCl  ·  Enzyme Inhibitor

Eflornithine HCl Monohydrate is a prescription enzyme inhibitor and the active ingredient in FDA-approved Vaniqa, a topical treatment approved for helping to reduce unwanted facial hair in women. It is designed to work by inhibiting ornithine decarboxylase (ODC), an enzyme found in hair follicles involved in cell division and hair growth. By inhibiting ODC activity, Eflornithine may help slow the rate at which hair grows back after removal, and over time may help reduce the thickness and texture of regrowth. It does not remove hair directly; it must be used alongside a hair removal method. Most patients may see noticeable results within 4 to 8 weeks of consistent use, though results vary.

Hair Removal Cream formula bottle

How It Works

ODC Inhibition  ·  Mechanism

Ornithine decarboxylase (ODC) is an enzyme found in the base of hair follicles that is involved in cell division and polyamine synthesis, both of which are factors in hair shaft production. Eflornithine is designed to inhibit this enzyme, which may help slow the cellular processes involved in hair growth. The intended result is a reduced regrowth rate and, with continued use, potentially finer and softer hair that may be easier to remove with your existing method. Results vary by individual.

How To Use

Application Guide  ·  Best Results

Apply to the affected area after hair removal. Your provider will give you specific instructions for when and how often to use. Hair may return to its previous growth rate if treatment is discontinued.

Hair Removal Cream formula texture

This information is for educational purposes only and is not a substitute for medical advice. Please consult your healthcare provider before starting or changing any medication.

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Clear skin results from DoctorDerm

Benefits

Why People Choose Hair Removal Cream

  • 01

    Designed to help slow hair regrowth at the follicle

    Eflornithine HCl is formulated to help inhibit ornithine decarboxylase, an enzyme involved in hair growth, which may help slow the rate of new growth at the root.

  • 02

    May help reduce hair thickness over time

    With consistent use, new hair may grow in thinner and softer, which could make your current removal method more effective and longer-lasting.

  • 03

    Designed to help extend time between removal sessions

    Applied after your regular hair removal method, it may help extend the time between treatments and may help reduce the frequency of maintenance.

  • 04

    Designed for facial use

    Specifically formulated for the upper lip, chin, and other areas of unwanted facial hair where regrowth is most noticeable.

  • 05

    Provider-prescribed for your skin

    A licensed provider reviews your case and prescribes your formula, no in-office visit or awkward consultations required.

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How It Works

Great skin shouldn't require a waiting room.

From your first question to your best skin. Here's how DoctorDerm works.

Step 1
01

Tell Us About Your Skin

Take a quick skin assessment. Upload a few photos. No appointments, no waiting rooms.

Step 2
02

A Real Provider Reviews Your Case

A provider personally reviews your results and builds your treatment plan. Made for your skin, no one else's.

Step 3
03

Your Prescription, Delivered

Your prescription treatment ships to your door every 60 days.

Step 4
04

Ongoing Care That Adapts

Adjust, check in, and get ongoing support whenever you need it.

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The Difference

Not all skincare is created equal.

See how DoctorDerm stacks up against the alternatives.

DoctorDerm Other Online Clinics In-Office Care
Prescription-grade formula
Real provider reviews your case
Personalized to your skinPartial
Ongoing provider support
No waiting room
Ships to your door

This comparison is based on publicly available information as of 2026. We encourage you to do your own research. We're just pretty confident you'll end up here anyway.

The only place you get real provider care, real prescriptions, and real ongoing support, without ever leaving home.

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Reviews

What Patients Are Saying

”I have been using Hair Removal Cream for months and I have noticed improvement. The regrowth seems slower and much finer. This was so easy, wish I had tried it before, definitely will keep buying.”

Verified Customer

”I came across Hair Removal Cream and after a few weeks of using it, I noticed the regrowth between appointments seemed less, and it felt easier to manage.”

Verified Customer

"I've been shaving since I was 16 and haven't found a long-term solution until now. Three months in and I've noticed less regrowth, the hair seems finer, and my skin feels smoother. Wish I had found this sooner."

Verified Customer

Rx-Grade

Prescription Formula

1,000+

Patients Treated

Licensed

Providers Only

Individual results may vary. Testimonials reflect personal experiences and do not guarantee outcomes.

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FAQ

Frequently Asked Questions

Most patients may notice slower regrowth within 4 to 8 weeks of consistent twice-daily use. Results are gradual and cumulative; continued use may lead to more noticeable results. Individual results vary.

No. Eflornithine HCl is designed to help slow the rate at which hair grows back after removal. It should be used alongside your regular hair removal method, such as shaving, threading, waxing, or laser, for best results.

Yes. All DoctorDerm formulas are prescription-grade and require a provider consultation. Your assessment is the first step.

This formula is specifically designed for facial use. Please mention any body hair concerns during your assessment.

Please inform your provider of your pregnancy or plans to become pregnant during the assessment. They will advise on whether this formula is appropriate for you.

Yes. Hair may return to its previous growth rate within 8 weeks of stopping treatment. Ongoing use is designed to help maintain results.

Yes. Eflornithine HCl is designed to complement laser hair removal by helping to slow regrowth between sessions, which may help extend the time between treatments.

DoctorDerm treatments combine ingredients into customized formulas that you typically wouldn’t receive as a single prescription in a traditional dermatology office. Our treatments are prepared and delivered directly to your door, giving you a complete skincare experience without the wait times or in-office visits.

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Ready to start with Hair Removal Cream?

$44.50/month. Billed as $89 every 2 months

Prescription-grade formula Provider-prescribed Free shipping Ongoing care
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Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider's prescription. Results may vary.